Study into conolidine has triggered discovery of the opioid receptor in the body termed ACKR3/CXCR7. ACKR3 appears to be probably the most sought after goal for conolidine, which also disregards one other four classical opioid receptors(3). Conolidine has become found in the tabernaemontana divaricata plant, that's during the Apocynaceae https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers