Ninety% of ibuprofen is metabolised to inactive compounds in the liver, mainly by glucuronidation, to produce two metabolites - a hydroxylated compound in addition to a carboxylated compound. Evident quantity of distribution is 0.fourteen L/kg. Ibuprofen and its metabolites easily cross the placental barrier in Expecting animals (rabbits and rats). https://ericj482qbh8.gynoblog.com/profile