Metabolic alterations related to T2D are very well characterised by epidemiological and research primarily based reports. The pathogenesis and progression of T2D is ascribed to four mechanisms; elevated advanced glycation conclusion merchandise (AGE) formation, improved polyol pathway flux, activation of protein kinase C (PKC) isoforms, and enhanced hexosamine pathway flux[7]. https://www.directivepublications.org/journal-of-diabetology-research/